PEA15 anticorps (pSer116)
Aperçu rapide pour PEA15 anticorps (pSer116) (ABIN1531370)
Antigène
Voir toutes PEA15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 81-130, pSer116
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Fonction
- PEA-15 (phospho Ser116) Antibody
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Specificité
- Phospho-PEA-15 (S116) Polyclonal Antibody detects endogenous levels of PEA-15 protein only when phosphorylated at S116.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human PEA-15 around the phosphorylation site of Ser116. AA range:81-130
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
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Autre désignation
- PEA-15
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Sujet
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Synonyms: PEA15, Astrocytic phosphoprotein PEA-15, 15 kDa phosphoprotein enriched in astrocytes, Phosphoprotein enriched in diabetes, PED
Background: phosphoprotein enriched in astrocytes 15(PEA15) Homo sapiens This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Gene Name: PEA15
Protein Name: Astrocytic phosphoprotein PEA-15
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Poids moléculaire
- 15 kDa
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ID gène
- 8682
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OMIM
- 603434
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UniProt
- Q15121
Antigène
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