PLK1 anticorps (pThr210)
Aperçu rapide pour PLK1 anticorps (pThr210) (ABIN1531376)
Antigène
Voir toutes PLK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 176-225, pThr210
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Fonction
- Plk (phospho Thr210) Antibody
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Specificité
- Phospho-Plk (T210) Polyclonal Antibody detects endogenous levels of Plk protein only when phosphorylated at T210.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210. AA range:176-225
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Isotype
- IgG
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Indications d'application
- WB 1:500-2000 ,IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PLK1 (Polo-Like Kinase 1 (PLK1))
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Autre désignation
- PLK1
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Sujet
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Synonyms: PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, PLK-1, Serine/threonine-protein kinase 13, STPK13
Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],
Gene Name: PLK1
Protein Name: Serine/threonine-protein kinase PLK1
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Poids moléculaire
- 68 kDa
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ID gène
- 5347
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OMIM
- 602098
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UniProt
- P53350
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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