Progesterone Receptor anticorps (pSer400)

N° du produit ABIN481991

L’anticorps anti-Progesterone Receptor Polyclonal Lapin est utilisé pour la détection de Progesterone Receptor dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et IHC.

Aperçu rapide pour Progesterone Receptor anticorps (pSer400) (ABIN481991)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Progesterone Receptor anticorps

Épitope: AA 371-420, pSer400

Fonction: PR (phospho Ser400) Antibody

Specificité: Phospho-PR (S400) Polyclonal Antibody detects endogenous levels of PR protein only when phosphorylated at S400.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser400. AA range:371-420

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: Progesterone Receptor

Sujet:

Synonyms: PGR, NR3C3, Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3

Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015],

Gene Name: PGR

Protein Name: Progesterone receptor

Poids moléculaire: 98 kDa

ID gène: 5241

OMIM: 607311

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration