Progesterone Receptor anticorps (AA 1-110)

N° du produit ABIN562204

Cet anticorps Souris Monoclonal détecte spécifiquement Progesterone Receptor dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.

Aperçu rapide pour Progesterone Receptor anticorps (AA 1-110) (ABIN562204)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5D10

Détail du produit anti-Progesterone Receptor anticorps

Épitope: AA 1-110

Fonction: Mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Séquence: MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Réactivité croisée: Humain, Rat

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-Progesterone Receptor (ABIN562204)

Liu, Chang, Kuo, Hwa, Lin, Huang, Chen, Chang, Hsieh: "Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System." dans: Cancer informatics, Vol. 11, pp. 87-111, (2012) (PubMed).

Liu, Chang, Kuo, Hwa, Shyu, Chang, Hsieh: "In Silico Prediction for Regulation of Transcription Factors onTheir Shared Target Genes Indicates Relevant Clinical Implications in a Breast Cancer Population." dans: Cancer informatics, Vol. 11, pp. 113-37, (2012) (PubMed).

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: PGR

Sujet: Full Gene Name: progesterone receptor
Synonyms: NR3C3,PR

ID gène: 5241

NCBI Accession: NM_000926

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration