SYN1 anticorps (pSer62)
Aperçu rapide pour SYN1 anticorps (pSer62) (ABIN1531398)
Antigène
Voir toutes SYN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-75, pSer62
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Fonction
- Synapsin I (phospho Ser62) Antibody
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Specificité
- Phospho-Synapsin I (S62) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S62.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human Synapsin1 around the phosphorylation site of Ser62. AA range:26-75
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- SYN1 (Synapsin I (SYN1))
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Autre désignation
- Synapsin1
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Sujet
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Synonyms: SYN1, Synapsin-1, Brain protein 4.1, Synapsin I
Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Gene Name: SYN1
Protein Name: Synapsin-1
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Poids moléculaire
- 73 kDa
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ID gène
- 6853
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OMIM
- 300491
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UniProt
- P17600
Antigène
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