NCF1 anticorps (pSer328)

N° du produit ABIN1531718

Il existe 1 publication pour ce produit. L’anticorps anti-NCF1 Polyclonal Lapin est utilisé pour la détection de NCF1 dans des échantillons de Humain, Souris, Rat et Boeuf (Vache). Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour NCF1 anticorps (pSer328) (ABIN1531718)

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-NCF1 anticorps

Épitope: AA 301-350, pSer328

Fonction: p47-phox (phospho Ser328) Antibody

Specificité: Phospho-p47-phox (S328) Polyclonal Antibody detects endogenous levels of p47-phox protein only when phosphorylated at S328.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Neutrophil Cytosol Factor 1 around the phosphorylation site of Ser328. AA range:301-350

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:10000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-NCF1 (ABIN1531718)

Kröller-Schön, Steven, Kossmann, Scholz, Daub, Oelze, Xia, Hausding, Mikhed, Zinßius, Mader, Stamm, Treiber, Scharffetter-Kochanek, Li, Schulz, Wenzel, Münzel, Daiber: "Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species - studies in white blood cells and in animal models." dans: Antioxidants & redox signaling, (2013) (PubMed).

Détails sur NCF1

Antigène: NCF1 (Neutrophil Cytosol Factor 1 (NCF1))

Autre désignation: Neutrophil Cytosol Factor 1

Sujet:

Synonyms: NCF1, NOXO2, SH3PXD1A, Neutrophil cytosol factor 1, NCF-1, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-47K, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox-organizing protein 2, SH3

Background: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008],

Gene Name: NCF1

Protein Name: Neutrophil cytosol factor 1

Poids moléculaire: 44 kDa

ID gène: 653361

OMIM: 233700

UniProt: P14598

Pathways: Signalisation PI3K-Akt