NCF1 anticorps (pSer370)
Aperçu rapide pour NCF1 anticorps (pSer370) (ABIN1531722)
Antigène
Voir toutes NCF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 341-390, pSer370
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Specificité
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p47 phox (Phospho-Ser370) Antibody detects endogenous levels of p47 phox only when phosphorylated at Ser370.
PhosphorylationH:S370 M:S370 R:S369
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Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser370.
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Isotype
- IgG
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Indications d'application
- IHC: 1:50~1:100 ELISA: 1:5000
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Commentaires
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Unigene-Number: Hs.647047, Hs.655201 (NCBI Gene Symbol: NCF1)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable at -20°C for at least 1 year.
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Date de péremption
- 12 months
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: "Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia." dans: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2016) (PubMed).
: "β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia." dans: Journal of neuroinflammation, Vol. 12, pp. 133, (2015) (PubMed).
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: "Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia." dans: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2016) (PubMed).
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- NCF1 (Neutrophil Cytosol Factor 1 (NCF1))
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Autre désignation
- p47 phox
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Sujet
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Synonyms: 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NCF-1, NCF-47K, NCF1, Neutrophil cytosol factor 1, Neutrophil cytosolic factor 1, Neutrophil NADPH oxidase factor 1, P47 phox, p47-phox
NCBI Gene Symbol: NCF1
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Poids moléculaire
- 44 kDa
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ID gène
- 653361
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OMIM
- 233700
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UniProt
- P14598
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Pathways
- Signalisation PI3K-Akt
Antigène
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