EPH Receptor A3 anticorps (pTyr779, pTyr833)

N° du produit ABIN1532042

Cet anticorps anti-EPH Receptor A3 Polyclonal Lapin (ABIN1532042) détecte spécifiquement EPH Receptor A3 dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour EPH Receptor A3 anticorps (pTyr779, pTyr833) (ABIN1532042)

Antigène: EPH Receptor A3 (EPHA3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor A3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-EPH Receptor A3 anticorps

Épitope: AA 746-795, pTyr779, pTyr833

Fonction: EphA3/4/5 (phospho Tyr779/833) Antibody

Specificité: Phospho-EphA3/4/5 (Y779/833) Polyclonal Antibody detects endogenous levels of EphA3/4/5 protein only when phosphorylated at Y779/833.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human EPHA3/4/5 around the phosphorylation site of Tyr779/833. AA range:746-795

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur EPH Receptor A3

Antigène: EPH Receptor A3 (EPHA3)

Autre désignation: EPHA3/4/5

Sujet:

Synonyms: EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1, EPHA4, HEK8, SEK, TYRO1, Ephri

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: EPHA3/EPHA4/EPHA5

Protein Name: Ephrin type-A receptor 3/4/5

Poids moléculaire: 110 kDa

ID gène: 2042, 2043, 54764

OMIM: 114500

UniProt: P29320

Pathways: Signalisation RTK, Regulation of Cell Size