PPARG anticorps (AA 78-127)
Aperçu rapide pour PPARG anticorps (AA 78-127) (ABIN1532398)
Antigène
Voir toutes PPARG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 78-127
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Fonction
- PPAR-γ Antibody
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Specificité
- PPAR-γ Polyclonal Antibody detects endogenous levels of PPAR-γ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human PPAR-gamma. AA range:78-127
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Isotype
- IgG
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Indications d'application
- IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
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Autre désignation
- PPAR-gamma
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Sujet
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Synonyms: PPARG, NR1C3, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
Background: peroxisome proliferator activated receptor gamma(PPARG) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma.The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008],
Gene Name: PPARG
Protein Name: Peroxisome proliferator-activated receptor gamma
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Poids moléculaire
- 57 kDa
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ID gène
- 5468
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OMIM
- 601487
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UniProt
- P37231
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Pathways
- Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Antigène
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