WASF1 anticorps (AA 91-140)

N° du produit ABIN1532430

L’anticorps anti-WASF1 Polyclonal Lapin est utilisé pour la détection de WASF1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour WASF1 anticorps (AA 91-140) (ABIN1532430)

Antigène: WASF1 (WAS Protein Family, Member 1 (WASF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WASF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-WASF1 anticorps

Épitope: AA 91-140

Fonction: WAVE1 Antibody

Specificité: WAVE1 Polyclonal Antibody detects endogenous levels of WAVE1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human WAVE1. AA range:91-140

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur WASF1

Antigène: WASF1 (WAS Protein Family, Member 1 (WASF1))

Autre désignation: WAVE1

Sujet:

Synonyms: WASF1, KIAA0269, SCAR1, WAVE1, Wiskott-Aldrich syndrome protein family member 1, WASP family protein member 1, Protein WAVE-1, Verprolin homology domain-containing protein 1

Background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: WASF1

Protein Name: Wiskott-Aldrich syndrome protein family member 1

Poids moléculaire: 61 kDa

ID gène: 8936

OMIM: 605035

UniProt: Q92558

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization