CSF1R anticorps (AA 781-830)

N° du produit ABIN1532577

Cet anticorps Lapin Polyclonal détecte spécifiquement CSF1R dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CSF1R anticorps (AA 781-830) (ABIN1532577)

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSF1R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CSF1R anticorps

Épitope: AA 781-830

Fonction: c-Fms Antibody

Specificité: C-Fms Polyclonal Antibody detects endogenous levels of c-Fms protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CSFR. AA range:781-830

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CSF1R

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSFR

Sujet:

Synonyms: CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD antigen CD115

Background: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Gene Name: CSF1R

Protein Name: Macrophage colony-stimulating factor 1 receptor

Poids moléculaire: 107 kDa

ID gène: 1436

OMIM: 164770

UniProt: P07333

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization