SAPK, JNK (AA 166-215) anticorps

N° du produit ABIN1532915

Cet anticorps anti-SAPK, JNK Polyclonal Lapin (ABIN1532915) détecte spécifiquement SAPK, JNK dans IHC, WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poisson et Porc.

Aperçu rapide pour SAPK, JNK (AA 166-215) anticorps (ABIN1532915)

Antigène: SAPK, JNK

Reactivité: Humain, Souris, Rat, Poisson, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit

Épitope: AA 166-215

Fonction: JNK1/2/3 Antibody

Specificité: JNK1/2/3 Polyclonal Antibody detects endogenous levels of JNK1/2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SAPK/JNK. AA range:166-215

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détail du antigène

Antigène: SAPK, JNK

Sujet:

Synonyms: MAPK8, JNK1, PRKM8, SAPK1, SAPK1C, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, SAPK1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, MAPK9, JNK2, PRKM9, SAPK1A, Mi

Background: The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl

Gene Name: MAPK8/9/10

Protein Name: Mitogen-activated protein kinase 8/9/10

Poids moléculaire: 48 kDa

ID gène: 5599, 5601, 5602

OMIM: 601158

UniProt: P45983