Claudin 1 anticorps (AA 162-211)

N° du produit ABIN1533224

Cet anticorps Lapin Polyclonal détecte spécifiquement Claudin 1 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Claudin 1 anticorps (AA 162-211) (ABIN1533224)

Antigène: Claudin 1 (CLDN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Claudin 1 anticorps

Épitope: AA 162-211

Fonction: Claudin-1 Antibody

Specificité: Claudin-1 Polyclonal Antibody detects endogenous levels of Claudin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Claudin 1. AA range:162-211

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Claudin 1

Antigène: Claudin 1 (CLDN1)

Autre désignation: Claudin 1

Sujet:

Synonyms: CLDN1, CLD1, SEMP1, Claudin-1, Senescence-associated epithelial membrane protein

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008],

Gene Name: CLDN1

Protein Name: Claudin-1

Poids moléculaire: 22 kDa

ID gène: 9076

OMIM: 603718

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C