Claudin 11 anticorps (AA 158-207)

N° du produit ABIN1533234

Il existe 1 publication pour ce produit. L’anticorps anti-Claudin 11 Polyclonal Lapin est utilisé pour la détection de Claudin 11 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour Claudin 11 anticorps (AA 158-207) (ABIN1533234)

Antigène: Claudin 11 (CLDN11)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 11 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Claudin 11 anticorps

Épitope: AA 158-207

Fonction: Claudin-11 Antibody

Specificité: Claudin-11 Polyclonal Antibody detects endogenous levels of Claudin-11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Claudin 11. AA range:158-207

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-Claudin 11 (ABIN1533234)

Mogk, Meiwes, Shtopel, Schraermeyer, Lazarus, Kubata, Wolburg, Duszenko: "Cyclical appearance of African trypanosomes in the cerebrospinal fluid: new insights in how trypanosomes enter the CNS." dans: PLoS ONE, Vol. 9, Issue 3, pp. e91372, (2014) (PubMed).

Détails sur Claudin 11

Antigène: Claudin 11 (CLDN11)

Autre désignation: Claudin 11

Sujet:

Synonyms: CLDN11, OSP, OTM, Claudin-11, Oligodendrocyte-specific protein

Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.The protein encoded by this gene is a major component of central nervous system (CNS) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis. This protein is a tight junction protein at the human blood-testis barrier (BTB), and the BTB disruption is related to a dysfunction of this gene. Alternatively spliced transcript variants encoding different iso

Gene Name: CLDN11

Protein Name: Claudin-11

Poids moléculaire: 21 kDa

ID gène: 5010

OMIM: 601326

UniProt: O75508

Pathways: Hepatitis C