Ephrin B3 anticorps (AA 221-270)
Aperçu rapide pour Ephrin B3 anticorps (AA 221-270) (ABIN1533263)
Antigène
Voir toutes Ephrin B3 (EFNB3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 221-270
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Fonction
- Ephrin-B3 Antibody
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Specificité
- Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human EFNB3. AA range:221-270
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Ephrin B3 (EFNB3)
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Autre désignation
- EFNB3
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Sujet
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Synonyms: EFNB3, EPLG8, LERK8, Ephrin-B3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, LERK-8
Background: EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the
Gene Name: EFNB3
Protein Name: Ephrin-B3
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Poids moléculaire
- 35 kDa
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ID gène
- 1949
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OMIM
- 602297
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UniProt
- Q15768
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Pathways
- Signalisation RTK
Antigène
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