Fibrillin 1 anticorps (AA 2811-2860)

N° du produit ABIN1533275

Cet anticorps Lapin Polyclonal détecte spécifiquement Fibrillin 1 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Fibrillin 1 anticorps (AA 2811-2860) (ABIN1533275)

Antigène: Fibrillin 1 (FBN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Fibrillin 1 anticorps

Épitope: AA 2811-2860

Fonction: FBN1 Antibody

Specificité: FBN1 Polyclonal Antibody detects endogenous levels of FBN1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Fibrillin-1. AA range:2811-2860

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Fibrillin 1

Antigène: Fibrillin 1 (FBN1)

Autre désignation: Fibrillin-1

Sujet:

Synonyms: FBN1, FBN, Fibrillin-1

Background: This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. [provided by RefSeq, Apr 2016],

Gene Name: FBN1

Protein Name: Fibrillin-1

Poids moléculaire: 312 kDa

ID gène: 2200

OMIM: 134797

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome