HSPD1 anticorps (AA 511-560)
Aperçu rapide pour HSPD1 anticorps (AA 511-560) (ABIN1533313)
Antigène
Voir toutes HSPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 511-560
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Fonction
- HSP60 Antibody
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Specificité
- HSP60 Polyclonal Antibody detects endogenous levels of HSP60 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human HSP60. AA range:511-560
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
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Autre désignation
- HSP60
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Sujet
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Synonyms: HSPD1, HSP60, 60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein
Background: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010],
Gene Name: HSPD1
Protein Name: 60 kDa heat shock protein mitochondrial
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Poids moléculaire
- 61 kDa
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ID gène
- 3329
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OMIM
- 118190
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UniProt
- P10809
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Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Antigène
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