RCC1 anticorps (AA 517-566)

N° du produit ABIN1533464

Cet anticorps anti-RCC1 Polyclonal Lapin (ABIN1533464) détecte spécifiquement RCC1 dans WB, IHC, IF et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RCC1 anticorps (AA 517-566) (ABIN1533464)

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCC1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-RCC1 anticorps

Épitope: AA 517-566

Fonction: XRCC1 Antibody

Specificité: XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RCC1

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Autre désignation: RCC1

Sujet:

Synonyms: XRCC1, DNA repair protein XRCC1, X-ray repair cross-complementing protein 1

Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Gene Name: XRCC1

Protein Name: DNA repair protein XRCC1

Poids moléculaire: 69 kDa

ID gène: 7515

OMIM: 194360

UniProt: P18887

Pathways: Chromatin Binding, Protein targeting to Nucleus