SKIL anticorps (AA 616-665)

N° du produit ABIN1533612

Cet anticorps Lapin Polyclonal détecte spécifiquement SKIL dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SKIL anticorps (AA 616-665) (ABIN1533612)

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKIL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SKIL anticorps

Épitope: AA 616-665

Fonction: SnoN Antibody

Specificité: SnoN Polyclonal Antibody detects endogenous levels of SnoN protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SKIL

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Autre désignation: SKIL

Sujet:

Synonyms: SKIL, SNO, Ski-like protein, Ski-related oncogene, Ski-related protein

Background: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

Gene Name: SKIL

Protein Name: Ski-like protein

Poids moléculaire: 77 kDa

ID gène: 6498

OMIM: 165340

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus