RORA anticorps (AA 6-55)
Aperçu rapide pour RORA anticorps (AA 6-55) (ABIN1533707)
Antigène
Voir toutes RORA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 6-55
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Fonction
- RORα Antibody
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Specificité
- RORα Polyclonal Antibody detects endogenous levels of RORα protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human RORA. AA range:6-55
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- RORA (RAR-Related Orphan Receptor A (RORA))
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Autre désignation
- RORA
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Sujet
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Synonyms: RORA, NR1F1, RZRA, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, Retinoid-related orphan receptor-alpha
Background: The protein encoded byThis gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014],
Gene Name: RORA
Protein Name: Nuclear receptor ROR-alpha
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Poids moléculaire
- 63 kDa
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ID gène
- 6095
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OMIM
- 600825
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UniProt
- P35398
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Antigène
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