ST5 anticorps (AA 411-460)
Aperçu rapide pour ST5 anticorps (AA 411-460) (ABIN1533807)
Antigène
Voir toutes ST5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 411-460
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Fonction
- ST5 Antibody
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Specificité
- ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human ST5. AA range:411-460
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Autre désignation
- ST5
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Sujet
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Synonyms: ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1
Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice.The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008],
Gene Name: ST5
Protein Name: Suppression of tumorigenicity 5 protein
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Poids moléculaire
- 126 kDa
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ID gène
- 6764
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OMIM
- 140750
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UniProt
- P78524
Antigène
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