TLE2 anticorps (AA 211-260)

N° du produit ABIN1533832

L’anticorps anti-TLE2 Polyclonal Lapin est utilisé pour la détection de TLE2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour TLE2 anticorps (AA 211-260) (ABIN1533832)

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TLE2 anticorps

Épitope: AA 211-260

Fonction: TLE2 Antibody

Specificité: TLE2 Polyclonal Antibody detects endogenous levels of TLE2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TLE2

Antigène: TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))

Autre désignation: TLE2

Sujet:

Synonyms: TLE2, Transducin-like enhancer protein 2, Enhancer of split groucho-like protein 2, ESG2

Background: function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 6 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5.,tissue specificity:In all tissues examined, mostly in heart, brain, and muscle.,

Gene Name: TLE2

Protein Name: Transducin-like enhancer protein 2

Poids moléculaire: 79 kDa

ID gène: 7089

OMIM: 601041

UniProt: Q04725

Pathways: Signalisation WNT