TLE4 anticorps (AA 161-210)

N° du produit ABIN1533833

Cet anticorps anti-TLE4 Polyclonal Lapin (ABIN1533833) détecte spécifiquement TLE4 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour TLE4 anticorps (AA 161-210) (ABIN1533833)

Antigène: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TLE4 anticorps

Épitope: AA 161-210

Fonction: TLE4 Antibody

Specificité: TLE4 Polyclonal Antibody detects endogenous levels of TLE4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TLE4. AA range:161-210

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TLE4

Antigène: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Autre désignation: TLE4

Sujet:

Synonyms: TLE4, KIAA1261, Transducin-like enhancer protein 4

Background: caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,

Gene Name: TLE4

Protein Name: Transducin-like enhancer protein 4

Poids moléculaire: 83 kDa

ID gène: 7091

OMIM: 605132

UniProt: Q04727

Pathways: Signalisation WNT