DUSP4 anticorps (AA 81-130)

N° du produit ABIN1533856

L’anticorps anti-DUSP4 Polyclonal Lapin est utilisé pour la détection de DUSP4 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour DUSP4 anticorps (AA 81-130) (ABIN1533856)

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DUSP4 anticorps

Épitope: AA 81-130

Fonction: MKP-2 Antibody

Specificité: MKP-2 Polyclonal Antibody detects endogenous levels of MKP-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human DUSP4. AA range:81-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DUSP4

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Autre désignation: DUSP4

Sujet:

Synonyms: DUSP4, MKP2, VH2, Dual specificity protein phosphatase 4, Dual specificity protein phosphatase hVH2, Mitogen-activated protein kinase phosphatase 2, MAP kinase phosphatase 2, MKP-2

Background: The protein encoded byThis gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been obser

Gene Name: DUSP4

Protein Name: Dual specificity protein phosphatase 4

Poids moléculaire: 42 kDa

ID gène: 1846

OMIM: 602747

UniProt: Q13115

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades