CHD4 anticorps (AA 571-620)
Aperçu rapide pour CHD4 anticorps (AA 571-620) (ABIN1533894)
Antigène
Voir toutes CHD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 571-620
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Fonction
- Mi2-β Antibody
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Specificité
- Mi2-β Polyclonal Antibody detects endogenous levels of Mi2-β protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CHD4. AA range:571-620
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Isotype
- IgG
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Indications d'application
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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Autre désignation
- CHD4
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Sujet
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Synonyms: CHD4, Chromodomain-helicase-DNA-binding protein 4, CHD-4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta
Background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Gene Name: CHD4
Protein Name: Chromodomain-helicase-DNA-binding protein 4
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Poids moléculaire
- 217 kDa
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ID gène
- 1108
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OMIM
- 603277
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UniProt
- Q14839
Antigène
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