STEAP2 anticorps (AA 431-480)

N° du produit ABIN1534012

L’anticorps anti-STEAP2 Polyclonal Lapin est utilisé pour la détection de STEAP2 dans des échantillons de Humain et Souris. Il a été validé pour IHC, ELISA, WB et IF.

Aperçu rapide pour STEAP2 anticorps (AA 431-480) (ABIN1534012)

Antigène: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-STEAP2 anticorps

Épitope: AA 431-480

Fonction: STEAP2 Antibody

Specificité: STEAP2 Polyclonal Antibody detects endogenous levels of STEAP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human STEA2. AA range:431-480

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur STEAP2

Antigène: STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))

Sujet:

Synonyms: STEAP2, PCANAP1, STAMP1, Metalloreductase STEAP2, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1

Background: STEAP2 metalloreductase(STEAP2) Homo sapiens This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Gene Name: STEAP2

Protein Name: Metalloreductase STEAP2

Poids moléculaire: 55 kDa

ID gène: 261729

OMIM: 605094

UniProt: Q8NFT2

Pathways: Transition Metal Ion Homeostasis