MKL1 anticorps (AA 10-59)

N° du produit ABIN1534057

Cet anticorps Lapin Polyclonal détecte spécifiquement MKL1 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MKL1 anticorps (AA 10-59) (ABIN1534057)

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MKL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MKL1 anticorps

Épitope: AA 10-59

Fonction: MRTF-A Antibody

Specificité: MRTF-A Polyclonal Antibody detects endogenous levels of MRTF-A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MKL1. AA range:10-59

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MKL1

Antigène: MKL1 (Megakaryoblastic Leukemia (Translocation) 1 (MKL1))

Autre désignation: MKL1

Sujet:

Synonyms: MKL1, KIAA1438, MAL, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein, Megakaryocytic acute leukemia protein, Myocardin-related transcription factor A, MRTF-A

Background: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

Gene Name: MKL1

Protein Name: MKL/myocardin-like protein 1

Poids moléculaire: 98 kDa

ID gène: 57591

OMIM: 606078

UniProt: Q969V6