CREBZF anticorps (AA 221-270)

N° du produit ABIN1534147

L’anticorps anti-CREBZF Polyclonal Lapin est utilisé pour la détection de CREBZF dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et IHC.

Aperçu rapide pour CREBZF anticorps (AA 221-270) (ABIN1534147)

Antigène: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREBZF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-CREBZF anticorps

Épitope: AA 221-270

Fonction: Zhangfei Antibody

Specificité: Zhangfei Polyclonal Antibody detects endogenous levels of Zhangfei protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CREBZF. AA range:221-270

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CREBZF

Antigène: CREBZF (CREB/ATF BZIP Transcription Factor (CREBZF))

Autre désignation: CREBZF

Sujet:

Synonyms: CREBZF, ZF, CREB/ATF bZIP transcription factor, Host cell factor-binding transcription factor Zhangfei, HCF-binding transcription factor Zhangfei

Background: function:Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.,miscellaneous:Named Zhangfei after a legendary Chinese warrior who was contemporary with Luman in around 220 AD.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subcellular location:Colocalizes at punctate nuclear structures with CREB3 and HCFC1.,subunit:Interacts with HCFC1, causing suppression of CREB3 transcriptional activity.,tissue specificity:In adults, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lungs. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.,

Gene Name: CREBZF

Protein Name: CREB/ATF bZIP transcription factor

Poids moléculaire: 28 kDa

ID gène: 58487

OMIM: 606444

UniProt: Q9NS37