MED23 anticorps (AA 1-50)

N° du produit ABIN1534191

Cet anticorps Lapin Polyclonal détecte spécifiquement MED23 dans ELISA, WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MED23 anticorps (AA 1-50) (ABIN1534191)

Antigène: MED23 (Mediator Complex Subunit 23 (MED23))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED23 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MED23 anticorps

Épitope: AA 1-50

Fonction: CRSP130 Antibody

Specificité: CRSP130 Polyclonal Antibody detects endogenous levels of CRSP130 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MED23. AA range:1-50

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MED23

Antigène: MED23 (Mediator Complex Subunit 23 (MED23))

Autre désignation: MED23

Sujet:

Synonyms: MED23, ARC130, CRSP3, DRIP130, KIAA1216, SUR2, Mediator of RNA polymerase II transcription subunit 23, Activator-recruited cofactor 130 kDa component, ARC130, Cofactor required for Sp1 transcriptional activation subunit 3, CRSP complex subu

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012],

Gene Name: MED23

Protein Name: Mediator of RNA polymerase II transcription subunit 23

Poids moléculaire: 156 kDa

ID gène: 9439

OMIM: 605042

UniProt: Q9ULK4

Pathways: Regulation of Lipid Metabolism by PPARalpha