IRAK3 anticorps (AA 491-540)

N° du produit ABIN1534222

L’anticorps anti-IRAK3 Polyclonal Lapin est utilisé pour la détection de IRAK3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour IRAK3 anticorps (AA 491-540) (ABIN1534222)

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRAK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IRAK3 anticorps

Épitope: AA 491-540

Fonction: IRAK-M Antibody

Specificité: IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IRAK3

Antigène: IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))

Autre désignation: IRAK3

Sujet:

Synonyms: IRAK3, Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M

Background: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],

Gene Name: IRAK3

Protein Name: Interleukin-1 receptor-associated kinase 3

Poids moléculaire: 67 kDa

ID gène: 11213

OMIM: 604459

UniProt: Q9Y616

Pathways: Signalisation TLR, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades