ADD2 anticorps (AA 471-520)

N° du produit ABIN1534258

L’anticorps anti-ADD2 Polyclonal Lapin est utilisé pour la détection de ADD2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour ADD2 anticorps (AA 471-520) (ABIN1534258)

Antigène: ADD2 (Adducin 2 (Beta) (ADD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ADD2 anticorps

Épitope: AA 471-520

Fonction: Adducin β Antibody

Specificité: Adducin β Polyclonal Antibody detects endogenous levels of Adducin β protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human ADD2. AA range:471-520

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ADD2

Antigène: ADD2 (Adducin 2 (Beta) (ADD2))

Autre désignation: ADD2

Sujet:

Synonyms: ADD2, ADDB, Beta-adducin, Erythrocyte adducin subunit beta

Background: adducin 2(ADD2) Homo sapiens Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region i

Gene Name: ADD2

Protein Name: Beta-adducin

Poids moléculaire: 80 kDa

ID gène: 119

OMIM: 102681

UniProt: P35612

Pathways: Regulation of Actin Filament Polymerization