Apoptosis Inhibitor 5 anticorps (AA 421-470)

N° du produit ABIN1534266

Cet anticorps Lapin Polyclonal détecte spécifiquement Apoptosis Inhibitor 5 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Apoptosis Inhibitor 5 anticorps (AA 421-470) (ABIN1534266)

Antigène: Apoptosis Inhibitor 5 (API5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Apoptosis Inhibitor 5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Apoptosis Inhibitor 5 anticorps

Épitope: AA 421-470

Fonction: API5 Antibody

Specificité: API5 Polyclonal Antibody detects endogenous levels of API5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Apoptosis Inhibitor 5

Antigène: Apoptosis Inhibitor 5 (API5)

Autre désignation: API-5

Sujet:

Synonyms: API5, MIG8, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, AAC-11, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL

Background: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Gene Name: API5

Protein Name: Apoptosis inhibitor 5

Poids moléculaire: 57 kDa

ID gène: 8539

OMIM: 609774

UniProt: Q9BZZ5

Pathways: Growth Factor Binding