Cadherin 4 anticorps (AA 731-780)

N° du produit ABIN1534296

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 4 dans IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Cadherin 4 anticorps (AA 731-780) (ABIN1534296)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Cadherin 4 anticorps

Épitope: AA 731-780

Fonction: R-cadherin Antibody

Specificité: R-cadherin Polyclonal Antibody detects endogenous levels of R-cadherin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4

Sujet:

Synonyms: CDH4, Cadherin-4, Retinal cadherin, R-CAD, R-cadherin

Background: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Gene Name: CDH4

Protein Name: Cadherin-4

Poids moléculaire: 100 kDa

ID gène: 1002

OMIM: 603006

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size