CDCA3 anticorps (AA 219-268)

N° du produit ABIN1534322

Cet anticorps anti-CDCA3 Polyclonal Lapin (ABIN1534322) détecte spécifiquement CDCA3 dans WB, IHC, IF et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CDCA3 anticorps (AA 219-268) (ABIN1534322)

Antigène: CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDCA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-CDCA3 anticorps

Épitope: AA 219-268

Fonction: CdcA3 Antibody

Specificité: CdcA3 Polyclonal Antibody detects endogenous levels of CdcA3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CDCA3

Antigène: CDCA3 (Cell Division Cycle Associated 3 (CDCA3))

Autre désignation: CDCA3

Sujet:

Synonyms: CDCA3, C8, GRCC8, TOME1, Cell division cycle-associated protein 3, Gene-rich cluster protein C8, Trigger of mitotic entry protein 1, TOME-1

Background: domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification, protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,

Gene Name: CDCA3

Protein Name: Cell division cycle-associated protein 3

Poids moléculaire: 28 kDa

ID gène: 83461

OMIM: 607749

UniProt: Q99618