GRID2 anticorps (AA 831-880)

N° du produit ABIN1534413

Cet anticorps Lapin Polyclonal détecte spécifiquement GRID2 dans WB, IF et ELISA. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GRID2 anticorps (AA 831-880) (ABIN1534413)

Antigène: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRID2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Détail du produit anti-GRID2 anticorps

Épitope: AA 831-880

Fonction: GluR-δ2 Antibody

Specificité: GluR-δ2 Polyclonal Antibody detects endogenous levels of GluR-δ2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human GRID2. AA range:831-880

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur GRID2

Antigène: GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

Autre désignation: GRID2

Sujet:

Synonyms: GRID2; GLURD2; Glutamate receptor delta-2 subunit; GluR delta-2 subunit

Background: The protein encoded byThis gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this

Gene Name: GRID2

Protein Name: Glutamate receptor delta-2 subunit

Poids moléculaire: 113 kDa

ID gène: 2895

OMIM: 602368

UniProt: O43424

Pathways: Synaptic Membrane