MLH1 anticorps (AA 441-490)

N° du produit ABIN1534468

L’anticorps anti-MLH1 Polyclonal Lapin est utilisé pour la détection de MLH1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour MLH1 anticorps (AA 441-490) (ABIN1534468)

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MLH1 anticorps

Épitope: AA 441-490

Fonction: MLH1 Antibody

Specificité: MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MLH1. AA range:441-490

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MLH1

Antigène: MLH1 (MutL Homolog 1 (MLH1))

Autre désignation: MLH1

Sujet:

Synonyms: MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

Gene Name: MLH1

Protein Name: DNA mismatch repair protein Mlh1

Poids moléculaire: 84 kDa

ID gène: 4292

OMIM: 120436

UniProt: P40692

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response