MSH2 anticorps (AA 541-590)

N° du produit ABIN1534471

L’anticorps anti-MSH2 Polyclonal Lapin est utilisé pour la détection de MSH2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, IF et ELISA.

Aperçu rapide pour MSH2 anticorps (AA 541-590) (ABIN1534471)

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSH2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-MSH2 anticorps

Épitope: AA 541-590

Fonction: MSH2 Antibody

Specificité: MSH2 Polyclonal Antibody detects endogenous levels of MSH2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MSH2

Antigène: MSH2 (Mismatch Repair Protein 2 (MSH2))

Autre désignation: MSH2

Sujet:

Synonyms: MSH2, DNA mismatch repair protein Msh2, hMSH2, MutS protein homolog 2

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

Gene Name: MSH2

Protein Name: DNA mismatch repair protein Msh2

Poids moléculaire: 104 kDa

ID gène: 4436

OMIM: 120435

UniProt: P43246

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response