MUTYH anticorps (AA 151-200)

N° du produit ABIN1534474

L’anticorps anti-MUTYH Polyclonal Lapin est utilisé pour la détection de MUTYH dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour MUTYH anticorps (AA 151-200) (ABIN1534474)

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUTYH est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MUTYH anticorps

Épitope: AA 151-200

Fonction: MYH Antibody

Specificité: MYH Polyclonal Antibody detects endogenous levels of MYH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MUTYH. AA range:151-200

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MUTYH

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Autre désignation: MUTYH

Sujet:

Synonyms: MUTYH, MYH, A/G-specific adenine DNA glycosylase, MutY homolog, hMYH

Background: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: MUTYH

Protein Name: A/G-specific adenine DNA glycosylase

Poids moléculaire: 60 kDa

ID gène: 4595

OMIM: 137215

UniProt: Q9UIF7

Pathways: Réparation de l'ADN