Neurofibromin 1 anticorps (AA 1551-1600)

N° du produit ABIN1534476

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurofibromin 1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Neurofibromin 1 anticorps (AA 1551-1600) (ABIN1534476)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Neurofibromin 1 anticorps

Épitope: AA 1551-1600

Fonction: Neurofibromin Antibody

Specificité: Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: NF1

Sujet:

Synonyms: NF1; Neurofibromin; Neurofibromatosis-related protein NF-1

Background: This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: NF1

Protein Name: Neurofibromin

Poids moléculaire: 319 kDa

ID gène: 4763

OMIM: 114500

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity