Claudin 19 anticorps (AA 81-130)

N° du produit ABIN1534781

Cet anticorps anti-Claudin 19 Polyclonal Lapin (ABIN1534781) détecte spécifiquement Claudin 19 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour Claudin 19 anticorps (AA 81-130) (ABIN1534781)

Antigène: Claudin 19 (CLDN19)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 19 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Claudin 19 anticorps

Épitope: AA 81-130

Fonction: Claudin-19 Antibody

Specificité: Claudin-19 Polyclonal Antibody detects endogenous levels of Claudin-19 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CLDN19. AA range:81-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Claudin 19

Antigène: Claudin 19 (CLDN19)

Autre désignation: CLDN19

Sujet:

Synonyms: CLDN19, Claudin-19

Background: The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010],

Gene Name: CLDN19

Protein Name: Claudin-19

Poids moléculaire: 23 kDa

ID gène: 149461

OMIM: 610036

UniProt: Q8N6F1

Pathways: Cell-Cell Junction Organization, Hepatitis C