Fibulin 5 anticorps (AA 171-220)
Aperçu rapide pour Fibulin 5 anticorps (AA 171-220) (ABIN1534905)
Antigène
Voir toutes Fibulin 5 (FBLN5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 171-220
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Fonction
- Fibulin-5 Antibody
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Specificité
- Fibulin-5 Polyclonal Antibody detects endogenous levels of Fibulin-5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Fibulin 5 (FBLN5)
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Autre désignation
- FBLN5
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Sujet
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Synonyms: FBLN5, DANCE, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Dance, Urine p50 protein, UP50
Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore,The protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008],
Gene Name: FBLN5
Protein Name: Fibulin-5
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Poids moléculaire
- 50 kDa
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ID gène
- 10516
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OMIM
- 604580
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UniProt
- Q9UBX5
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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