OAZ1 anticorps (AA 14-63)

N° du produit ABIN1535135

Cet anticorps anti-OAZ1 Polyclonal Lapin (ABIN1535135) détecte spécifiquement OAZ1 dans IHC, WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour OAZ1 anticorps (AA 14-63) (ABIN1535135)

Antigène: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAZ1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-OAZ1 anticorps

Épitope: AA 14-63

Fonction: AZ1 Antibody

Specificité: AZ1 Polyclonal Antibody detects endogenous levels of AZ1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human OAZ1. AA range:14-63

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:40000,WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur OAZ1

Antigène: OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))

Autre désignation: OAZ1

Sujet:

Synonyms: OAZ1, OAZ, Ornithine decarboxylase antizyme 1, ODC-Az

Background: The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit.This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms

Gene Name: OAZ1

Protein Name: Ornithine decarboxylase antizyme 1

Poids moléculaire: 25 kDa

ID gène: 4946

OMIM: 601579

UniProt: P54368