SGOL2 anticorps (AA 681-730)

N° du produit ABIN1535371

L’anticorps anti-SGOL2 Polyclonal Lapin est utilisé pour la détection de SGOL2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, IF et IHC.

Aperçu rapide pour SGOL2 anticorps (AA 681-730) (ABIN1535371)

Antigène: SGOL2 (Shugoshin-Like 2 (SGOL2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGOL2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-SGOL2 anticorps

Épitope: AA 681-730

Fonction: Sgo2 Antibody

Specificité: Sgo2 Polyclonal Antibody detects endogenous levels of Sgo2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SGOL2

Antigène: SGOL2 (Shugoshin-Like 2 (SGOL2))

Autre désignation: SGOL2

Sujet:

Synonyms: SGOL2, Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin

Background: function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,

Gene Name: SGOL2

Protein Name: Shugoshin-like 2

Poids moléculaire: 144 kDa

ID gène: 151246

OMIM: 612425

UniProt: Q562F6