UBE3B anticorps (AA 581-630)

N° du produit ABIN1535449

L’anticorps anti-UBE3B Polyclonal Lapin est utilisé pour la détection de UBE3B dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour UBE3B anticorps (AA 581-630) (ABIN1535449)

Antigène: UBE3B (Ubiquitin Protein Ligase E3B (UBE3B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE3B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-UBE3B anticorps

Épitope: AA 581-630

Fonction: UBE3B Antibody

Specificité: UBE3B Polyclonal Antibody detects endogenous levels of UBE3B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human UBE3B. AA range:581-630

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur UBE3B

Antigène: UBE3B (Ubiquitin Protein Ligase E3B (UBE3B))

Autre désignation: UBE3B

Sujet:

Synonyms: UBE3B, Ubiquitin-protein ligase E3B

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases.This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [pro

Gene Name: UBE3B

Protein Name: Ubiquitin-protein ligase E3B

Poids moléculaire: 123 kDa

ID gène: 89910

OMIM: 608047

UniProt: Q7Z3V4