Histone H2B anticorps (AA 10-59)

N° du produit ABIN1535536

L’anticorps anti-Histone H2B Polyclonal Lapin est utilisé pour la détection de Histone H2B dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour Histone H2B anticorps (AA 10-59) (ABIN1535536)

Antigène: Histone H2B

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Histone H2B anticorps

Épitope: AA 10-59

Fonction: Histone H2B Antibody

Specificité: Histone H2B Polyclonal Antibody detects endogenous levels of Histone H2B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:10-59

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Histone H2B

Antigène: Histone H2B

Sujet:

Synonyms: H2BFS, Histone H2B type F-S, Histone H2B.s, H2B/s

Background: H2BFS is a Pseudogene. Histone H2B type 1-H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. Diseases associated with H2BFS include endometrial stromal sarcoma. Among its related pathways are Packaging Of Telomere Ends. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BH.

Gene Name: H2BFS

Protein Name: Histone H2B type F-S

Poids moléculaire: 13 kDa

ID gène: 54145

UniProt: P57053