PTH1R anticorps (AA 145-194)
Aperçu rapide pour PTH1R anticorps (AA 145-194) (ABIN1535655)
Antigène
Voir toutes PTH1R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 145-194
-
Fonction
- PTH/PTHrP-R Antibody
-
Specificité
- PTH/PTHrP-R Polyclonal Antibody detects endogenous levels of PTH/PTHrP-R protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Pureté
- > 95 %
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human PTHR1. AA range:145-194
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
-
Autre désignation
- PTHR1
-
Sujet
-
Synonyms: PTH1R; PTHR; PTHR1; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor
Background: The protein encoded byThis gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],
Gene Name: PTH1R
Protein Name: Parathyroid hormone/parathyroid hormone-related peptide receptor
-
Poids moléculaire
- 52 kDa
-
ID gène
- 5745
-
OMIM
- 168468
-
UniProt
- Q03431
-
Pathways
- Regulation of Carbohydrate Metabolic Process
Antigène
-