HRH1 anticorps (AA 141-190)

N° du produit ABIN1535758

L’anticorps anti-HRH1 Polyclonal Lapin est utilisé pour la détection de HRH1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour HRH1 anticorps (AA 141-190) (ABIN1535758)

Antigène: HRH1 (Histamine Receptor H1 (HRH1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-HRH1 anticorps

Épitope: AA 141-190

Fonction: Histamine H1 Receptor Antibody

Specificité: Histamine H1 Receptor Polyclonal Antibody detects endogenous levels of Histamine H1 Receptor protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human HRH1. AA range:141-190

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HRH1

Antigène: HRH1 (Histamine Receptor H1 (HRH1))

Autre désignation: HRH1

Sujet:

Synonyms: HRH1, Histamine H1 receptor, H1R, HH1R

Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4.The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref

Gene Name: HRH1

Protein Name: Histamine H1 receptor

Poids moléculaire: 55 kDa

ID gène: 3269

OMIM: 600167

UniProt: P35367

Pathways: Regulation of Carbohydrate Metabolic Process