OPN4 anticorps (AA 429-478)

N° du produit ABIN1535846

Cet anticorps anti-OPN4 Polyclonal Lapin (ABIN1535846) détecte spécifiquement OPN4 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour OPN4 anticorps (AA 429-478) (ABIN1535846)

Antigène: OPN4 (Opsin 4 (OPN4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPN4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-OPN4 anticorps

Épitope: AA 429-478

Fonction: Melanopsin Antibody

Specificité: Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human OPN4. AA range:429-478

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur OPN4

Antigène: OPN4 (Opsin 4 (OPN4))

Autre désignation: OPN4

Sujet:

Synonyms: OPN4, MOP, Melanopsin, Opsin-4

Background: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily.This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by Ref

Gene Name: OPN4

Protein Name: Melanopsin

Poids moléculaire: 52 kDa

ID gène: 94233

OMIM: 606665

UniProt: Q9UHM6