OPRK1 anticorps (AA 321-370)

N° du produit ABIN1535849

Cet anticorps anti-OPRK1 Polyclonal Lapin (ABIN1535849) détecte spécifiquement OPRK1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris et Singe.

Aperçu rapide pour OPRK1 anticorps (AA 321-370) (ABIN1535849)

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPRK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-OPRK1 anticorps

Épitope: AA 321-370

Fonction: KOR-1 Antibody

Specificité: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur OPRK1

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Autre désignation: OPRK1

Sujet:

Synonyms: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1

Background: This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],

Gene Name: OPRK1

Protein Name: Kappa-type opioid receptor

Poids moléculaire: 42 kDa

ID gène: 4986

OMIM: 165196

UniProt: P41145