NOTCH2 anticorps (Cleaved-Asp1733)

N° du produit ABIN1536095

Cet anticorps anti-NOTCH2 Polyclonal Lapin (ABIN1536095) détecte spécifiquement NOTCH2 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NOTCH2 anticorps (Cleaved-Asp1733) (ABIN1536095)

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-NOTCH2 anticorps

Épitope: AA 1684-1733, Cleaved-Asp1733

Fonction: Cleaved-Notch 2 (D1733) Antibody

Specificité: Cleaved-Notch 2 (D1733) Polyclonal Antibody detects endogenous levels of fragment of activated Notch 2 protein resulting from cleavage adjacent to D1733.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Notch 2. AA range:1684-1733

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NOTCH2

Antigène: NOTCH2 (Notch 2 (NOTCH2))

Autre désignation: Notch 2

Sujet:

Synonyms: NOTCH2, Neurogenic locus notch homolog protein 2, Notch 2, hN2

Background: notch 2(NOTCH2) Homo sapiens This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cle

Gene Name: NOTCH2

Protein Name: Neurogenic locus notch homolog protein 2

Poids moléculaire: 100 and 130 kDa

ID gène: 4853

OMIM: 600275

UniProt: Q04721

Pathways: Signalisation Notch, Stem Cell Maintenance